Dimenhydrinate interferes with radioimmunoassay of theophylline.

Anaphylaxis to dimenhydrinate caused by the theophylline component.

A simple, solid-phase iodine-125 radioimmunoassay for theophylline.

The activity of y-glutamyltransferase (EC 2.3.2.2) is measured on the DuPont aca by an adaptation of the Szasz procedure ;-y-glutamyl-p-nitroanilide is transferred to glycylglycine, thereby releasing p-nitroaniline, which is measured at 405 nm. I have noticed low glutamyltransfer-ase activity in patients with cholestasis wherealkaline phosphate (EC 3.1.3.1) is increased, total bilirubin> 100 mg...

ModifiedAcetonitrileProtein- PrecipItatIonMethodof Sample Preparationfor DrugAssayby LiquidChromatography

serious toxicity other than some nausea. Continued treatment with intravenous theophylline resulted in compensation of her respiratory difficulties. In its literature, Clinical Assays mentions that 8-chlorotheophylline may interfere. Dimenhydrinate is the 8chlorotheophylline salt of the antihistaminic diphenhydrammne. In addition to the theophylline peak on chromatography, there was another pea...

Dimenhydrinate use for children with vomiting.

QUESTION Dimenhydrinate is an over-the-counter drug that is commonly used for the treatment of nausea and vomiting. Many of my adult patients use it, but is it safe and useful in the pediatric population? ANSWER Dimenhydrinate appears to be safe for use in the pediatric population. While little literature has been published about adverse effects of this medication, family physicians need to i...

Urticaria caused by dimenhydrinate.